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Gene/ORF F37C12.4 (rpl-36) Ace View of F37C12.4
F37C12.4 Details Help
Description  rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates.
Homology Group (KOG)  60S ribosomal protein L36
GO Terms  structural constituent of ribosome (GO:0003735) ; protein biosynthesis (GO:0006412) ; intracellular (GO:0005622) ; ribosome (GO:0005840)
Location   III:7179775..7181400
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects ; Severe Pleiotropic Defects ; Severe Pleiotropic Defects
Postembryonic Larval Arrest-Early (L1/L2)
Larva Lva ; Gro ; Gro
Adult Sck ; Sterile F0/Fertility Problems ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:310-h8
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:310-h8 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:311-a2
Adult Phenotypes  Sterile F0/Fertility Problems
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:311-a2 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:329-h10
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:329-h10 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:341-a6
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type Cenix:341-a6 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F37C12.4
Adult Phenotypes  Sck
Ste
RNAi Reagent Name & Type sjj_F37C12.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F37C12.4
Embryonic Phenotypes  Emb Penetrance 20 - 40 %
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_F37C12.4 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:311a2
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:311a2 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (F37C12.4-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:341a6
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:341a6 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (F37C12.4-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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