Ace View of F41C6.1 | |||
F41C6.1 Details | |||
Description | unc-6 encodes a netrin orthologous to the human and mouse netrin-1 precursor proteins; UNC-6 functions as a guidance molecule that regulates the migrations of pioneer axons and mesodermal cells, such as the gonadal distal tip cell, along the dorsoventral axis; a secreted molecule, UNC-6 is expressed during embryogenesis by epidermoblasts and neurons; UNC-6 is involved in both attractive and repulsive interactions that are mediated by the UNC-40 and UNC-5 netrin receptors, respectively. | ||
Homology Group (KOG) | Netrin, axonal chemotropic factor |
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GO Terms | mesoderm cell migration (GO:0008078) ; axon guidance (GO:0007411) ; cytoplasm (GO:0005737) ; axon (GO:0030424) ; receptor binding (GO:0005102) ; extracellular matrix (GO:0005578) ; structural molecule activity (GO:0005198) | ||
Location | X:6889241..6897488 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Cenix:60-b10 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:60-b10 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | 3/3 tests are wildtype. | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
JA:F41C6.1 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_F41C6.1 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Simmer:F41C6.1:Repeat_a | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_F41C6.1 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Simmer:F41C6.1:Repeat_b | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_F41C6.1 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Simmer:F41C6.1:Screen | |||
Adult Phenotypes | Unc
could not be confirmed by re-testing |
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RNAi Reagent Name & Type | sjj_F41C6.1 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Gene Plot of F41C6.1 | |||