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Gene/ORF F41C6.1 (unc-6) Ace View of F41C6.1
F41C6.1 Details Help
Description  unc-6 encodes a netrin orthologous to the human and mouse netrin-1 precursor proteins; UNC-6 functions as a guidance molecule that regulates the migrations of pioneer axons and mesodermal cells, such as the gonadal distal tip cell, along the dorsoventral axis; a secreted molecule, UNC-6 is expressed during embryogenesis by epidermoblasts and neurons; UNC-6 is involved in both attractive and repulsive interactions that are mediated by the UNC-40 and UNC-5 netrin receptors, respectively.
Homology Group (KOG)  Netrin, axonal chemotropic factor
GO Terms  mesoderm cell migration (GO:0008078) ; axon guidance (GO:0007411) ; cytoplasm (GO:0005737) ; axon (GO:0030424) ; receptor binding (GO:0005102) ; extracellular matrix (GO:0005578) ; structural molecule activity (GO:0005198)
Location   X:6889241..6897488
RNAi Phenotypes
Adult Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Simmer:F41C6.1:Repeat_b WT
Cenix:60-b10 WT
Simmer:F41C6.1:Repeat_a WT
JA:F41C6.1 WT
Experiments with Non-Wild Phenotypes
Simmer:F41C6.1:Screen Unc
Gene Plot of F41C6.1 Browse using GBrowse
Gene Map