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Gene/ORF F42A6.7 (hrp-1) Ace View of F42A6.7
F42A6.7 Details Help
Description  The hrp-1 gene encodes a homolog of the human DRPLA gene (OMIM:125370), which when mutated leads to dentatorubral-pallidoluysian atrophy or to Haw River syndrome (OMIM:140340).
GO Terms  nucleotide binding (GO:0000166) ; nucleic acid binding (GO:0003676)
Location   IV:3336535..3339259
RNAi Phenotypes
Postembryonic Larval Arrest-Late (L3/L4)
Larva Lva ; Gro ; Gro
Adult Sck
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Larval Phenotypes  Gro
Adult Phenotypes  Sck
RNAi Reagent Name & Type sjj_F42A6.7 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F42A6.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Adult Phenotypes  Larval Arrest-Late (L3/L4)
RNAi Reagent Name & Type Cenix:41-b1 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No reproducible early defects. Chromosome segregation defects observed at four cell stage in one of the experiments.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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