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Gene/ORF F43C1.2 (mpk-1) Ace View of F43C1.2
F43C1.2 Details Help
Description  mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro.
Homology Group (KOG)  Mitogen-activated protein kinase
GO Terms  MAP kinase activity (GO:0004707) ; ATP binding (GO:0005524) ; protein amino acid phosphorylation (GO:0006468) ; protein kinase activity (GO:0004672) ; protein serine/threonine kinase activity (GO:0004674)
Location   III:4216334..4228464
RNAi Phenotypes
Postembryonic aldicarb_resistant
Larva Let ; Let ; Let
Adult Pvl ; Sterile F0/Fertility Problems ; Ste ; Ste ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
TH:307H1 WT
Cenix:307-h1 WT
WBRNAi00060160 WT
Experiments with Non-Wild Phenotypes
TH:334d1 Ste
Simmer:F43C1.2 Emb
Cenix:334-d1
WBRNAi00060161 aldicarb_resistant
Cenix:341-h5 Sterile F0/Fertility Problems
WBRNAi00060162 Let
TH:341h5 Ste
TH:303h3 Ste
WBRNAi00060163 Let
Cenix:303-h3
JA:F43C1.2 Emb ; Ste
Gene Plot of F43C1.2 Browse using GBrowse
Gene Map