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Gene/ORF F45E12.2 (brf-1) Ace View of F45E12.2
F45E12.2 Details Help
Description  brf-1 encodes an ortholog of mammalian B-RELATED FACTOR (also known as BRF, TDS4, PCF4, or hTFIIIB90); BRF is thought to act as a molecular bridge between TATA-binding protein (TBP) associated factors that functions in TFIIIB (RNA polymerase III associated transcription factors).
Homology Group (KOG)  Transcription initiation factor TFIIIB, Brf1 subunit
GO Terms  zinc ion binding (GO:0008270) ; transcriptional activator activity (GO:0016563) ; positive regulation of transcription (GO:0045941) ; nucleus (GO:0005634) ; transcription factor activity (GO:0003700) ; transcription initiation (GO:0006352) ; regulation of transcription, DNA-dependent (GO:0006355) ; transcription factor complex (GO:0005667)
Location   II:7305394..7309013
RNAi Phenotypes
Postembryonic Larval Arrest-Late (L3/L4)
Larva Lva ; Lva
Adult Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:F45E12.4 WT
JA:F45E12.2 WT
Experiments with Non-Wild Phenotypes
PF:GL1_5H8 Stp
Simmer:F45E12.2:Repeat_a Lva
Cenix:13-f10 Larval Arrest-Late (L3/L4)
Simmer:F45E12.2:Screen Lva
Gene Plot of F45E12.2 Browse using GBrowse
Gene Map