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Gene/ORF F45F2.2 (his-39) Ace View of F45F2.2
F45F2.2 Details Help
Description  his-39 encodes an H2B histone; by homology, HIS-39 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; loss of his-39 function via RNA-mediated interference (RNAi) does not result in any abnormalities; his-39 is a replication-dependent histone locus that resides in the HIS2 cluster on chromosome V.
Homology Group (KOG)  Histone H2B
GO Terms  DNA binding (GO:0003677) ; nucleosome assembly (GO:0006334) ; chromosome organization and biogenesis (sensu Eukarya) (GO:0007001) ; nucleosome (GO:0000786) ; nucleus (GO:0005634)
Location   V:8538502..8539704
RNAi Phenotypes
Early_embryo Sister Chromatid Separation abnormal (Cross-eyed)
Larva Lva ; Lva ; Lva ; Gro
Adult Unc ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:F45F2.2
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F45F2.2 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F45F2.2:Repeat_a
Embryonic Phenotypes  Emb Penetrance 90 %
Larval Phenotypes  Lva
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_F45F2.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F45F2.2:Screen
Embryonic Phenotypes  Emb Penetrance 90 %
Larval Phenotypes  Lva
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_F45F2.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of F45F2.2 Browse using GBrowse
Gene Map