Ace View of F46A9.4 | |||||||||
F46A9.4 Details | |||||||||
Description | skr-2 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-2 is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis; SKR-2::GFP is detected exclusively in the intestine. | ||||||||
Homology Group (KOG) | SCF ubiquitin ligase, Skp1 component |
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GO Terms | negative regulation of cell proliferation (GO:0008285) ; pachytene (GO:0000239) ; mitotic spindle orientation (GO:0000132) ; embryonic development (sensu Animalia) (GO:0009792) ; SCF ubiquitin ligase complex (GO:0019005) ; molecular_function unknown (GO:0005554) | ||||||||
Location | I:9469280..9471023 | ||||||||
RNAi Phenotypes |
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External Links | |||||||||
Associated RNAi Experiments | |||||||||
Experiments with Non-Wild Phenotypes | |||||||||
Cenix:16-h1 | Emb ; WT_postembryonic_morphology | ||||||||
Simmer:F46A9.4:Screen_B | Emb | ||||||||
PF:GL1_3A2 | Egl ; Emb ; Gon | ||||||||
JA:F46A9.4 | Emb ; Gro ; Pvl ; Spn ; Unc | ||||||||
Simmer:F46A9.4:Screen_A | Emb ; Lva ; Unc | ||||||||
Gene Plot of F46A9.4 | |||||||||