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Gene/ORF F46A9.5 (skr-1) Ace View of F46A9.5
F46A9.5 Details Help
Description  The skr-1 gene encodes a homolog of Skp1 in S. cerevisiae that is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis.
Homology Group (KOG)  SCF ubiquitin ligase, Skp1 component
Location   I:9471135..9473032
RNAi Phenotypes
Early_embryo P0 spindle positioning problems ; Abnormal blebbing ; Ectopic furrows ; Polar bodies abnormal ; Multiple nuclei
Postembryonic WT_postembryonic_morphology
Larva Gro
Adult Pvl ; Pvl ; Lon ; Lon ; Ste ; Rup
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:F30A10.1
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F30A10.1 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Simmer:F30A10.1:Repeat_b
Adult Phenotypes  Lon
RNAi Reagent Name & Type sjj_F30A10.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F30A10.1:Screen_A
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F30A10.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F30A10.1:Screen_B
Adult Phenotypes  Lon
RNAi Reagent Name & Type sjj_F30A10.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
JA:F46A9.5
Embryonic Phenotypes  Emb Penetrance 90 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F46A9.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F46A9.5:Screen_A
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Pvl
Rup
Adult Phenotypes  Unclassified Thin
RNAi Reagent Name & Type sjj_F46A9.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F46A9.5:Screen_B
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_F46A9.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Cenix:184-c10
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:184-c10 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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