Ace View of F46F3.1 | |||
F46F3.1 Details | |||
Description | ceh-27 encodes a homeodomain protein of the NK-2 class that contains Drosophila scarecrow and human NKX-2 (OMIM:606727); CEH-27 activity is essential for embryogenesis and appears to be required for maintaining hypodermal integrity during movement as embryos lacking CEH-27 burst at a breach in the ventral hypodermis upon commencement of muscle contractions; CEH-27 expression is first detected in the ~100-cell embryo in what appear to be MS-derived cells while in later embryos expression is seen in a number of cells in the anterior head region. | ||
Homology Group (KOG) | Transcription factor tinman/NKX2-3, contains HOX domain |
||
GO Terms | DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; regulation of transcription (GO:0045449) | ||
Location | V:11663860..11667687 | ||
RNAi Phenotypes |
|
||
External Links | |||
Associated RNAi Experiments | |||
Cenix:41-e2 | |||
Embryonic Phenotypes | Emb Penetrance None reported | ||
Adult Phenotypes | WT_postembryonic_morphology |
||
RNAi Reagent Name & Type | Cenix:41-e2 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | early embryonic: No significant defects seen. | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Gene Plot of F46F3.1 | |||