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Gene/ORF F52B5.5 (cep-1) Ace View of F52B5.5
F52B5.5 Details Help
Description  cep-1 encodes an ortholog of the human tumor suppressor p53 (OMIM:191170, mutated in Li-Fraumeni syndrome) that promotes DNA damage-induced apoptosis and is required for normal meiotic segregation in the germ line, and affects sensitivity to hypoxia-induced lethality and longevity in response to starvation; CEP-1 is expressed ubiquitously in embryos and in the nucleoli of a subset of pharyngeal cells.
GO Terms  DNA damage response, signal transduction resulting in induction of apoptosis (GO:0008630) ; meiotic chromosome segregation (GO:0045132) ; response to stress (GO:0006950) ; regulation of transcription (GO:0045449) ; nucleus (GO:0005634) ; nucleolus (GO:0005730) ; transcription factor activity (GO:0003700) ; DNA binding (GO:0003677) ; zinc ion binding (GO:0008270)
Location   I:8323711..8329241
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:87-h1 WT
Cenix:96-c5 WT
JA:F52B5.4 WT
JA:F52B5.5 WT
Gene Plot of F52B5.5 Browse using GBrowse
Gene Map