Ace View of F52B5.5 | |
F52B5.5 Details | |
Description | cep-1 encodes an ortholog of the human tumor suppressor p53 (OMIM:191170, mutated in Li-Fraumeni syndrome) that promotes DNA damage-induced apoptosis and is required for normal meiotic segregation in the germ line, and affects sensitivity to hypoxia-induced lethality and longevity in response to starvation; CEP-1 is expressed ubiquitously in embryos and in the nucleoli of a subset of pharyngeal cells. |
GO Terms | DNA damage response, signal transduction resulting in induction of apoptosis (GO:0008630) ; meiotic chromosome segregation (GO:0045132) ; response to stress (GO:0006950) ; regulation of transcription (GO:0045449) ; nucleus (GO:0005634) ; nucleolus (GO:0005730) ; transcription factor activity (GO:0003700) ; DNA binding (GO:0003677) ; zinc ion binding (GO:0008270) |
Location | I:8323711..8329241 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Wild Type RNAi Experiments | |
Cenix:87-h1 | WT |
Cenix:96-c5 | WT |
JA:F52B5.4 | WT |
JA:F52B5.5 | WT |
Gene Plot of F52B5.5 | |