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Gene/ORF F53A2.4 (nud-1) Ace View of F53A2.4
F53A2.4 Details Help
Description  nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
Homology Group (KOG)  Nuclear distribution protein NUDC
Location   III:13340643..13342508
RNAi Phenotypes
Early_embryo Slow cell cycle ; Osmotic Integrity defective ; Pnm ; Large cytoplasmic granules ; Abnormal size of pronucleus ; Rot ; Multiple maternal pronuclei ; Osmotically/ pressure sensitive
Postembryonic Evl ; WT_postembryonic_morphology
Larva Gro ; Gro ; Gro
Adult Reduced fecundity of injected worm ; Pvl ; Ste ; Unc ; Unc ; Rup ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:320-a8
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:320-a8 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F53A2.4
Embryonic Phenotypes  Emb Penetrance 80 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F53A2.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_5H12
Embryonic Phenotypes  Emb Penetrance 80 - 100 %
Larval Phenotypes  Gro Observed in >=10% of progeny.
Adult Phenotypes  Ste
Reduced fecundity of injected worm
Adult Phenotypes  Abnormal size of pronucleus
Large cytoplasmic granules
Multiple maternal pronuclei
Osmotically/ pressure sensitive
Slow cell cycle
RNAi Reagent Name & Type sjj_F53A2.4 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif
Simmer:F53A2.4
Embryonic Phenotypes  Emb Penetrance 20 - 40 %
Larval Phenotypes  Gro
Adult Phenotypes  Pvl
Rup
Unc
Adult Phenotypes  Unclassified Thin
RNAi Reagent Name & Type sjj_F53A2.4 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:320A8
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:320A8 (PCR reagent)
Remark  Phenotype comment -- Phenotype confirmed by second independent RNA (RNA2).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:342B1
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:342B1 (PCR reagent)
Remark  Phenotype comment -- Phenotype confirmed by second independent RNA (RNA2).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
[cgc4895]nud-1
Embryonic Phenotypes  Emb Penetrance 73 %
Adult Phenotypes  Stp
Unc
Adult Phenotypes  Evl
Pnm
Rot
RNAi Reagent Name & Type [cgc4895]nud-1 (PCR reagent)
Delivery Method  Injection
Laboratory  UA
Date  2001-8-31
Reference  Dawe AL et al. (2001) Development Genes & Evolution "Evolutionarily conserved nuclear migration genes required for early embryonic ...."
Cenix:342-b1
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:342-b1 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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