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Gene/ORF F54C9.5 (rpl-5) Ace View of F54C9.5
F54C9.5 Details Help
Description  rpl-5 encodes a large ribosomal subunit L5 protein; by homology, RPL-5 is predicted to function in protein biosynthesis; in C. elegans RPL-5 activity is broadly required for embryonic, larval, germline, and vulval development, as well as normal body coloration, morphology, and postembryonic growth rates.
Homology Group (KOG)  60S ribosomal protein L5
GO Terms  structural constituent of ribosome (GO:0003735) ; protein biosynthesis (GO:0006412) ; intracellular (GO:0005622) ; ribosome (GO:0005840) ; 5S rRNA binding (GO:0008097)
Location   II:8569449..8571362
RNAi Phenotypes
Early_embryo Catastrophic one-cell arrest ; Embryos arrest at different stages ; Severe Pleiotropic Defects
Postembryonic Pch
Larva Lva ; Lva ; Gro
Adult Dpy ; Egg production ceases in injected animal ; Pvl ; Ste ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:18-g6
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:18-g6 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F54C9.5
Embryonic Phenotypes  Emb Penetrance 80 %
Larval Phenotypes  Gro
Adult Phenotypes  Dpy
Pvl
Ste
Adult Phenotypes  Pch
RNAi Reagent Name & Type sjj_F54C9.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F54C9.5
Larval Phenotypes  Lva
Adult Phenotypes  Ste brood size (6 out of 10)
RNAi Reagent Name & Type sjj_F54C9.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of F54C9.5 Browse using GBrowse
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