Ace View of F54C9.6 | |||||
F54C9.6 Details | |||||
Description | F54C9.6 encodes a protein orthologous to the human mitochondrial protein BCS1 (YEAST HOMOLOG)-LIKE (BCS1L; OMIM:603647); mutation of BCS1L leads to neonatal tubulopathy, encephalopathy, and liver failure, or to GRACILE syndrome. | ||||
GO Terms | nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524) | ||||
Location | II:8570620..8573202 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Cenix:148-f4 | |||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||
RNAi Reagent Name & Type | Cenix:148-f4 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | 20-30% embryonic lethality. All escapers arrest at late larval stage. | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:F54C9.6 | |||||
Larval Phenotypes | Gro |
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Adult Phenotypes | Clr |
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RNAi Reagent Name & Type | sjj_F54C9.6 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
PF:GL1_8C8 | |||||
Embryonic Phenotypes | Emb Penetrance 25 - 50 % | ||||
Larval Phenotypes | Gro
Observed in >=10% of progeny. Lva Observed in >=10% of progeny. |
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RNAi Reagent Name & Type | sjj_F54C9.6 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | PCR product contains flanking T7 promoter sequences | ||||
Laboratory | KK | ||||
Date | 2002-11-19 | ||||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||||
Simmer:F54C9.6 | |||||
Larval Phenotypes | Gro |
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RNAi Reagent Name & Type | sjj_F54C9.6 (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Gene Plot of F54C9.6 | |||||