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Gene/ORF F54C9.6 Ace View of F54C9.6
F54C9.6 Details Help
Description  F54C9.6 encodes a protein orthologous to the human mitochondrial protein BCS1 (YEAST HOMOLOG)-LIKE (BCS1L; OMIM:603647); mutation of BCS1L leads to neonatal tubulopathy, encephalopathy, and liver failure, or to GRACILE syndrome.
GO Terms  nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524)
Location   II:8570620..8573202
RNAi Phenotypes
Larva Lva ; Gro ; Gro ; Gro
Adult Clr
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:148-f4
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type Cenix:148-f4 (PCR reagent)
Delivery Method  Injection
Remark  20-30% embryonic lethality. All escapers arrest at late larval stage.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F54C9.6
Larval Phenotypes  Gro
Adult Phenotypes  Clr
RNAi Reagent Name & Type sjj_F54C9.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_8C8
Embryonic Phenotypes  Emb Penetrance 25 - 50 %
Larval Phenotypes  Gro Observed in >=10% of progeny.
Lva Observed in >=10% of progeny.
RNAi Reagent Name & Type sjj_F54C9.6 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Simmer:F54C9.6
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F54C9.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of F54C9.6 Browse using GBrowse
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