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Gene/ORF F54F7.5 (mes-1) Ace View of F54F7.5
F54F7.5 Details Help
Description  The mes-1 gene encodes a receptor tyrosine kinase-like protein that is required for unequal cell divisions in the early embryonic germline; during embryonic cell divisions, mes-1 is involved in positioning of the early mitotic spindle and of associated P granules.
GO Terms  asymmetric cytokinesis (GO:0008356) ; cell fate specification (GO:0001708) ; establishment and/or maintenance of cell polarity (GO:0007163) ; mitotic spindle positioning and orientation (GO:0040001) ; gametogenesis (GO:0007276) ; asymmetric protein localization involved in cell fate commitment (GO:0045167) ; integral to plasma membrane (GO:0005887) ; protein-tyrosine kinase activity (GO:0004713) ; protein kinase activity (GO:0004672) ; ATP binding (GO:0005524) ; protein amino acid phosphorylation (GO:0006468)
Location   X:11857016..11862695
RNAi Phenotypes
Adult Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:53-g11
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:53-g11 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects seen in any of the recordings.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F54F7.5
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F54F7.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
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