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Gene/ORF F56H1.4 (rpt-5) Ace View of F56H1.4
F56H1.4 Details Help
Description  rpt-5 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-5 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
Homology Group (KOG)  26S proteasome regulatory complex, ATPase RPT5
GO Terms  hydrolase activity (GO:0016787) ; protein catabolism (GO:0030163) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737) ; nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524)
Location   I:5741471..5743976
RNAi Phenotypes
Early_embryo Catastrophic one-cell arrest ; Ocs ; Osmotically/ pressure sensitive ; Passage Through Meiosis defective
Larva Lvl
Adult Reduced fecundity of injected worm ; Ste ; Ste ; Ste ; No developing embryos seen 48 hours after dsRNA injection
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
JA:F56H1.4 Emb ; Ocs ; Ste
Simmer:F56H1.4:Screen_B Emb
Cenix:148-h6 Emb ; Passage Through Meiosis defective
Simmer:F56H1.4:Screen_A Emb ; Ste
PF:GL1_4E9 Catastrophic one-cell arrest ; Emb ; Osmotically/ pressure sensitive ; Ste ; No developing embryos seen 48 hours after dsRNA injection ; Reduced fecundity of injected worm
Gene Plot of F56H1.4 Browse using GBrowse
Gene Map