Ace View of F56H1.4 | |
F56H1.4 Details | |
Description | rpt-5 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-5 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome. |
Homology Group (KOG) | 26S proteasome regulatory complex, ATPase RPT5 |
GO Terms | hydrolase activity (GO:0016787) ; protein catabolism (GO:0030163) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737) ; nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524) |
Location | I:5741471..5743976 |
RNAi Phenotypes | |
External Links | |
Associated RNAi Experiments | |
Cenix:148-h6 | |
Embryonic Phenotypes | Emb Penetrance None reported |
Adult Phenotypes | Passage Through Meiosis defective |
RNAi Reagent Name & Type | Cenix:148-h6 (PCR reagent) |
Delivery Method | Injection |
Remark | early embryonic: Passage Through Meiosis |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
JA:F56H1.4 | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Ste
brood size range (1 out of 5) |
Adult Phenotypes | Ocs
1-12 cell arrest |
RNAi Reagent Name & Type | sjj_F56H1.4 (PCR reagent) |
Laboratory | JA |
Date | 2000-11-16 |
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | Movies/Stacks/Images |
PF:GL1_4E9 | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Ste No developing embryos seen 48 hours after dsRNA injection Reduced fecundity of injected worm |
Adult Phenotypes | Catastrophic one-cell arrest Osmotically/ pressure sensitive |
RNAi Reagent Name & Type | sjj_F56H1.4 (PCR reagent) |
Delivery Method | Injection |
Remark | PCR product contains flanking T7 promoter sequences |
Laboratory | KK |
Date | 2002-11-19 |
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | Movies/Stacks/Images |
Simmer:F56H1.4:Screen_A | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Ste
brood size (6 out of 10) |
RNAi Reagent Name & Type | sjj_F56H1.4 (PCR reagent) |
Laboratory | NL |
Date | 2003-10-01 |
Strain | NL4256 rrf-3(pk1426) |
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Simmer:F56H1.4:Screen_B | |
Embryonic Phenotypes | Emb Penetrance 100 % |
RNAi Reagent Name & Type | sjj_F56H1.4 (PCR reagent) |
Laboratory | NL |
Date | 2003-10-01 |
Strain | NL4256 rrf-3(pk1426) |
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Gene Plot of F56H1.4 | |