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Gene/ORF F57B10.12 (mei-2) Ace View of F57B10.12
F57B10.12 Details Help
Description  mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1
GO Terms  embryonic development (GO:0009790) ; meiotic spindle assembly (GO:0000212) ; microtubule depolymerization (GO:0007019) ; spindle pole (GO:0000922) ; condensed nuclear chromosome (GO:0000794) ; protein binding (GO:0005515)
Location   I:6564350..6566253
RNAi Phenotypes
Early_embryo Mei ; Passage Through Meiosis defective
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:F57B10.12:Screen_A Emb
JA:F57B10.12 Emb ; Mei
Simmer:F57B10.12:Screen_B Emb
Cenix:86-e8 Emb ; Passage Through Meiosis defective
Gene Plot of F57B10.12 Browse using GBrowse
Gene Map