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Gene/ORF F58B6.3 (par-2) Ace View of F58B6.3
F58B6.3 Details Help
Description  par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3.
GO Terms  asymmetric protein localization involved in cell fate commitment (GO:0045167) ; asymmetric cytokinesis (GO:0008356) ; mitotic spindle orientation (GO:0000132) ; cell cortex (GO:0005938) ; zinc ion binding (GO:0008270) ; ATP binding (GO:0005524) ; ubiquitin-protein ligase activity (GO:0004842) ; protein ubiquitination (GO:0016567) ; ubiquitin ligase complex (GO:0000151)
Location   III:1080992..1095435
RNAi Phenotypes
Early_embryo Asymmetry of Division abnormal ; Spo
Adult Muv ; Pvl ; Ste ; Rup
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
JA:F58B6.3 Emb ; Muv ; Pvl ; Rup
Simmer:F58B6.3 Emb
Cenix:238-a3 Asymmetry of Division abnormal ; Emb
Gene Plot of F58B6.3 Browse using GBrowse
Gene Map