Ace View of F58E10.2 | |
F58E10.2 Details | |
Description | end-1 encodes a GATA-like transcription factor sufficient to initiate endoderm differentiation and binds to the canonical target DNA sequence WGATAR with specificity similar to GATA-1 and D4 transcription factors; its expression bypasses requirement for maternal SKN-1 and the maternal Wnt signaling pathway in endoderm formation and it activates endoderm differentiation in isolated Xenopus ectoderm. |
Homology Group (KOG) | GATA-4/5/6 transcription factors |
GO Terms | endoderm cell fate determination (GO:0007493) ; transcriptional activator activity (GO:0016563) ; DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) |
Location | V:13987326..13989989 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Cenix:49-g8 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:49-g8 (PCR reagent) |
Delivery Method | Injection |
Remark | 3/3 tests are wildtype. |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
JA:F58E10.2 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | sjj_F58E10.2 (PCR reagent) |
Laboratory | JA |
Date | 2003-1-10 |
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Gene Plot of F58E10.2 | |