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Link to F58E10.2RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF F58E10.2 (end-1) Ace View of F58E10.2
F58E10.2 Details Help
Description  end-1 encodes a GATA-like transcription factor sufficient to initiate endoderm differentiation and binds to the canonical target DNA sequence WGATAR with specificity similar to GATA-1 and D4 transcription factors; its expression bypasses requirement for maternal SKN-1 and the maternal Wnt signaling pathway in endoderm formation and it activates endoderm differentiation in isolated Xenopus ectoderm.
Homology Group (KOG)  GATA-4/5/6 transcription factors
GO Terms  endoderm cell fate determination (GO:0007493) ; transcriptional activator activity (GO:0016563) ; DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634)
Location   V:13987326..13989989
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:49-g8
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:49-g8 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F58E10.2
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F58E10.2 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of F58E10.2 Browse using GBrowse
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