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Gene/ORF F58E6.10 (unc-42) Ace View of F58E6.10
F58E6.10 Details Help
Description  unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
GO Terms  DNA binding (GO:0003677) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; regulation of transcription (GO:0045449)
Location   V:9766828..9772252
RNAi Phenotypes
Adult Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:126-d9 WT
JA:F58E6.10 WT
Experiments with Non-Wild Phenotypes
Simmer:F58E6.10:Screen Unc
Simmer:F58E6.10:Repeat_a Unc
Gene Plot of F58E6.10 Browse using GBrowse
Gene Map