Ace View of F59E12.2 | |||||
F59E12.2 Details | |||||
Description | zyg-1 encodes a homolog of polo-like and calcium-dependent kinases that is required for daughter centriole formation; ZYG-1 localizes transiently to centrosomes and acts at least one cell cycle prior to each spindle assembly event; ZYG-1 activity is required for proper localization of the SAS-5 and SAS-6 coiled-coil proteins that are also required for centriole duplication. | ||||
Homology Group (KOG) | Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily |
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GO Terms | cell division (GO:0051301) ; reproduction (GO:0000003) ; centriole replication (GO:0007099) ; mitotic spindle assembly (GO:0051227) ; embryonic development (sensu Animalia) (GO:0009792) ; protein localization (GO:0008104) ; centrosome (GO:0005813) ; protein kinase activity (GO:0004672) ; ATP binding (GO:0005524) ; protein amino acid phosphorylation (GO:0006468) ; protein-tyrosine kinase activity (GO:0004713) | ||||
Location | II:5649318..5654792 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Experiments with Non-Wild Phenotypes | |||||
[cgc4699]:zyg-1 | Emb ; Stp ; Unc | ||||
Cenix:148-e8 | Emb ; Spindle Assembly abnormal | ||||
JA:F59E12.2 | Emb | ||||
Gene Plot of F59E12.2 | |||||