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Gene/ORF H04J21.3 (gip-1) Ace View of H04J21.3
H04J21.3 Details Help
Description  gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization.
Location   III:2347179..2362440
RNAi Phenotypes
Early_embryo Spindle Assembly abnormal ; Spindle Assembly abnormal
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:H04J21.3 WT
Experiments with Non-Wild Phenotypes
Cenix:341-b7
TH:341b7 Emb
Cenix:140-a1 Emb ; Spindle Assembly abnormal
TH:338a3 Emb
Cenix:338-a3 Emb ; Spindle Assembly abnormal
Gene Plot of H04J21.3 Browse using GBrowse
Gene Map