Gene/ORF
H04J21.3 (gip-1)
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Ace View of H04J21.3
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H04J21.3 Details |
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Description |
gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. |
Location |
III:2347179..2362440 |
RNAi Phenotypes |
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External Links |
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Associated RNAi Experiments |
View Details
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Wild Type RNAi Experiments |
JA:H04J21.3 |
WT |
Experiments with Non-Wild Phenotypes |
Cenix:341-b7 |
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TH:341b7 |
Emb |
Cenix:140-a1 |
Emb ; Spindle Assembly abnormal |
TH:338a3 |
Emb |
Cenix:338-a3 |
Emb ; Spindle Assembly abnormal |
Gene Plot of H04J21.3 |
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