Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to H26D21.2RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF H26D21.2 (msh-2) Ace View of H26D21.2
H26D21.2 Details Help
Description  The msh-2 gene encodes a DNA mismatch repair protein homolog that is orthologous to human MSH2 (OMIM:120435); mutation of the human MSH2 gene leads to hereditary non-polyposis colon cancer (OMIM:120436).
Homology Group (KOG)  Mismatch repair ATPase MSH2 (MutS family)
GO Terms  DNA binding (GO:0003677) ; ATP binding (GO:0005524) ; mismatch repair (GO:0006298) ; nucleus (GO:0005634) ; damaged DNA binding (GO:0003684) ; DNA metabolism (GO:0006259)
Location   I:3693916..3697951
RNAi Phenotypes
Postembryonic Mut
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:140-b2
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:140-b2 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:H26D21.2
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_H26D21.2 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Gene Plot of H26D21.2 Browse using GBrowse
Gene Map