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Gene/ORF K02F6.9 Ace View of K02F6.9
K02F6.9 Details Help
Description  K02F6.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; K02F6.9 has no clear orthologs in other organisms.
Homology Group (KOG)  M13 family peptidase
GO Terms  metallopeptidase activity (GO:0008237) ; zinc ion binding (GO:0008270) ; proteolysis and peptidolysis (GO:0006508) ; neprilysin activity (GO:0004245) ; membrane (GO:0016020)
Location   II:2557430..2564078
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:79-b7
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:79-b7 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests give wildtype results.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K02F6.9
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_K02F6.9 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of K02F6.9 Browse using GBrowse
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