Ace View of K02F6.9 | |
K02F6.9 Details | |
Description | K02F6.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; K02F6.9 has no clear orthologs in other organisms. |
Homology Group (KOG) | M13 family peptidase |
GO Terms | metallopeptidase activity (GO:0008237) ; zinc ion binding (GO:0008270) ; proteolysis and peptidolysis (GO:0006508) ; neprilysin activity (GO:0004245) ; membrane (GO:0016020) |
Location | II:2557430..2564078 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Cenix:79-b7 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:79-b7 (PCR reagent) |
Delivery Method | Injection |
Remark | 3/3 tests give wildtype results. |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
JA:K02F6.9 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | sjj_K02F6.9 (PCR reagent) |
Laboratory | JA |
Date | 2003-1-10 |
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Gene Plot of K02F6.9 | |