| Gene/ORF
K05F1.2 (msp-142)
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Ace View of K05F1.2
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| K05F1.2 Details |
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| Description |
msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| GO Terms |
structural molecule activity
(GO:0005198) |
| Location |
II:5797464..5798705 |
| RNAi Phenotypes |
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| External Links |
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| Associated RNAi Experiments |
View Details
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Cenix:206-e1
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| Adult Phenotypes |
WT
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| RNAi Reagent Name & Type |
Cenix:206-e1 (PCR reagent) |
| Delivery Method |
Injection |
| Remark |
Wildtype results in all three tests. |
| Laboratory |
TH |
| Date |
2005-3-24 |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Gene Plot of K05F1.2 |
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