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Gene/ORF K06A5.7 (cdc-25.1) Ace View of K06A5.7
K06A5.7 Details Help
Description  cdc-25.1 encodes a CDC25 phosphatase homolog that affects embryonic viability, meiosis, mitosis, proliferation of the intestine (E cell lineage), and germ line proliferation; it is expressed in the developing germline, in the nuclei of oocytes, embryonic nuclei, nuclei of embryonic cortical membranes, and sperm pronuclei, and in the germline precursors Z2 and Z3.
Homology Group (KOG)  M-phase inducer phosphatase
GO Terms  cell proliferation (GO:0008283) ; nucleus (GO:0005634) ; protein phosphatase activity (GO:0004721) ; protein tyrosine phosphatase activity (GO:0004725) ; M phase of mitotic cell cycle (GO:0000087) ; protein amino acid dephosphorylation (GO:0006470) ; intracellular (GO:0005622)
Location   I:6468988..6472353
RNAi Phenotypes
Early_embryo Passage Through Meiosis defective
Adult Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:75-a6
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Passage Through Meiosis defective
RNAi Reagent Name & Type Cenix:75-a6 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Passage Through Meiosis
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K06A5.7
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_K06A5.7 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Simmer:K06A5.7:Screen_A
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Ste
RNAi Reagent Name & Type sjj_K06A5.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:K06A5.7:Screen_B
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_K06A5.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of K06A5.7 Browse using GBrowse
Gene Map