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Gene/ORF K10D2.6 (emb-8) Ace View of K10D2.6
K10D2.6 Details Help
Description  Uncloned locus required for embryonic viability, for the normal generation of anterior-posterior asymmetry in the early embryo, and for normal P Granule and GLP-1 asymmetry in early embryos.
Homology Group (KOG)  NADP/FAD dependent oxidoreductase
GO Terms  oxidoreductase activity (GO:0016491) ; electron transport (GO:0006118) ; FMN binding (GO:0010181) ; electron transporter activity (GO:0005489)
Location   III:5196244..5200036
RNAi Phenotypes
Early_embryo Osmotic Integrity defective ; Osmotic Integrity defective
Larva Lva ; Gro ; Gro
Adult Ooc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:310-b9
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:310-b9 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:311-c2
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:311-c2 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:329-e11
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:329-e11 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
TH:310B9
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:310B9 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:311C2
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:311C2 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:329E11
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:329E11 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Cenix:303-e9
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:303-e9 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:341-e1
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:341-e1 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K10D2.6
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_K10D2.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:K10D2.6
Embryonic Phenotypes  Emb Penetrance 50 - 80 %
Larval Phenotypes  Gro
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_K10D2.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:303e9
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:303e9 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (K10D2.6 -RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:341e1
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:341e1 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (K10D2.6 -RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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