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Gene/ORF K12D12.2 (npp-3) Ace View of K12D12.2
K12D12.2 Details Help
Description  npp-3 encodes a predicted nucleoporin that is a homolog of vertebrate Nup205, and is required for normal nuclear pore complex distribution in the nuclear envelope, affects nuclear exclusion of large non-nuclear macromolecules, chromatin condensation, early embryonic viability, body integrity and locomotion.
Homology Group (KOG)  Uncharacterized conserved protein
GO Terms  porin activity (GO:0015288)
Location   II:11865029..11874999
RNAi Phenotypes
Early_embryo Sister Chromatid Separation abnormal (Cross-eyed)
Adult Clr ; Unc ; Rup
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:201-b12
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Sister Chromatid Separation abnormal (Cross-eyed)
RNAi Reagent Name & Type Cenix:201-b12 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K12D12.3
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_K12D12.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Cenix:200-a7
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:200-a7 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K12D12.2
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Clr
Rup
Unc
RNAi Reagent Name & Type sjj_K12D12.2 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of K12D12.2 Browse using GBrowse
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