Ace View of K12D12.2 | |||||
K12D12.2 Details | |||||
Description | npp-3 encodes a predicted nucleoporin that is a homolog of vertebrate Nup205, and is required for normal nuclear pore complex distribution in the nuclear envelope, affects nuclear exclusion of large non-nuclear macromolecules, chromatin condensation, early embryonic viability, body integrity and locomotion. | ||||
Homology Group (KOG) | Uncharacterized conserved protein |
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GO Terms | porin activity (GO:0015288) | ||||
Location | II:11865029..11874999 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Cenix:201-b12 | |||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||
Adult Phenotypes | Sister Chromatid Separation abnormal (Cross-eyed) |
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RNAi Reagent Name & Type | Cenix:201-b12 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | early embryonic: Sister Chromatid Separation (Cross-eyed) | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:K12D12.3 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_K12D12.3 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Cenix:200-a7 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:200-a7 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | 3/3 tests are wildtype. | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:K12D12.2 | |||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||
Adult Phenotypes | Clr Rup Unc |
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RNAi Reagent Name & Type | sjj_K12D12.2 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Gene Plot of K12D12.2 | |||||