Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to K12H4.5.2Link to K12H4.5.1Link to K12H4.4.1Link to K12H4.4.2Link to K12H4.3RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF K12H4.4 Ace View of K12H4.4
K12H4.4 Details Help
Homology Group (KOG)  Signal peptidase complex subunit
GO Terms  signal peptidase activity (GO:0009003) ; signal peptide processing (GO:0006465) ; signal peptidase complex (GO:0005787) ; integral to membrane (GO:0016021)
Location   III:8044530..8046255
RNAi Phenotypes
Early_embryo Osmotic Integrity defective
Postembryonic Prz ; WT_postembryonic_morphology ; Larval Lethal-Early (L1/L2) ; Larval Lethal-Early (L1/L2)
Larva Let ; Mlt ; Lvl ; Gro
Adult Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:310-e4
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Osmotic Integrity defective
RNAi Reagent Name & Type Cenix:310-e4 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Osmotic Integrity
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:340-b6
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:340-b6 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:K12H4.4
Larval Phenotypes  Gro
Lvl
Mlt
Adult Phenotypes  Ste
Adult Phenotypes  Prz
RNAi Reagent Name & Type sjj_K12H4.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:K12H4.4
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_K12H4.4 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:310E4
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:310E4 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (K12H4.4-RNA2; less penetrant DIC phenotype, partial embryonic lethal); not confirmed with third dsRNA (K12H4.4-RNA3).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:340B6
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:340B6 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (K12H4.4-RNA2; less penetrant DIC phenotype, partial embryonic lethal); not confirmed with third dsRNA (K12H4.4-RNA3).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of K12H4.4 Browse using GBrowse
Gene Map