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Gene/ORF M106.1 (mix-1) Ace View of M106.1
M106.1 Details Help
Description  The mix-1 gene encodes a homolog of SMC2 involved in chromosome segregation, X-chromosome gene regulation, and repression of X-linked genes during dosage compensation.
Homology Group (KOG)  Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E)
GO Terms  dosage compensation, by hypoactivation of X chromosome (GO:0042464) ; mitotic chromosome segregation (GO:0000070) ; mitotic chromosome condensation (GO:0007076) ; condensed chromosome (GO:0000793) ; transcription regulator activity (GO:0030528) ; ATP binding (GO:0005524) ; chromosome organization and biogenesis (GO:0051276) ; chromosome (GO:0005694) ; protein binding (GO:0005515)
Location   II:10823808..10841721
RNAi Phenotypes
Early_embryo Sister Chromatid Separation abnormal (Cross-eyed) ; Aberrant nuclear reassembly ; Ectopic cleavage furrows ; Cytokinesis defect ; Abnormal size of pronucleus ; Polar body reabsorbed ; Aberrant cell-cell contacts at the four-cell stage ; Nuclei reform next to cell division remnant
Larva Let
Adult Sck
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
JA:R06F6.10 Emb
Cenix:10-b5 Emb ; Sister Chromatid Separation abnormal (Cross-eyed)
PF:GL1_6D8 Aberrant cell-cell contacts at the four-cell stage ; Aberrant nuclear reassembly ; Abnormal size of pronucleus ; Cytokinesis defect ; Ectopic cleavage furrows ; Emb ; Nuclei reform next to cell division remnant ; Polar body reabsorbed
JA:M106.1 Emb
Gene Plot of M106.1 Browse using GBrowse
Gene Map