Gene/ORF
R06C7.7 (lin-61)
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Ace View of R06C7.7
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R06C7.7 Details |
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Description |
lin-61 encodes a protein that contains mbt repeats and has similarity to the Drosophila Polycomb group protein Sex Comb on Midleg and human protein H-l-(3)mbl-like; by homology, LIN-61 is predicted to function as part of a transcriptional regulatory complex that may play a role in transcriptional repression during development; loss of lin-61 activity via RNAi and forward mutations indicates that LIN-61 is required for: 1) genome stability in the soma and germline, and 2) postembryonic developmental processes such as vulval development, in which lin-61 acts as a class B synthetic multivulval (SynMuv) gene. |
Homology Group (KOG) |
Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)
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GO Terms |
regulation of transcription
(GO:0045449) ; nucleus
(GO:0005634) |
Location |
I:7248428..7251653 |
RNAi Phenotypes |
No phenotypes observed.
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External Links |
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Associated RNAi Experiments |
View Details
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Wild Type RNAi Experiments |
JA:R06C7.7 |
WT |
Cenix:149-d4 |
WT |
PF:GL1_6D11 |
WT |
Gene Plot of R06C7.7 |
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