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Gene/ORF R119.6 (taf-4) Ace View of R119.6
R119.6 Details Help
Description  taf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis.
Homology Group (KOG)  TATA box binding protein (TBP)-associated factor, RNA polymerase II
Location   I:382118..388904
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology
Larva Lva ; Lvl ; Gro
Adult Unc ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:R119.6 WT
Experiments with Non-Wild Phenotypes
Simmer:R119.6:Screen_A Emb ; Gro ; Ste ; Unc
Simmer:R119.6:Screen_B Emb ; Lva ; Lvl
Cenix:199-b7 Emb ; WT_postembryonic_morphology
Gene Plot of R119.6 Browse using GBrowse
Gene Map