ORF Card Page


Gene/ORF R11G10.1 (avr-15)	Ace View of R11G10.1
R11G10.1 Details
Description	avr-15 encodes, via alternative splicing, two glutamate-gated chloride channel subunit homologs; these proteins mediate fast inhibitory glutamatergic neuromuscular transmission, as well as ivermectin sensitivity, and are required for normal pharyngeal function.
Homology Group (KOG)	Ligand-gated ion channel
GO Terms	GABA-A receptor activity (GO:0004890) ; extracellular ligand-gated ion channel activity (GO:0005230) ; ion transport (GO:0006811) ; integral to membrane (GO:0016021) ; postsynaptic membrane (GO:0045211) ; neurotransmitter receptor activity (GO:0030594) ; membrane (GO:0016020) ; transport (GO:0006810)
Location	V:13501008..13514710
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Summary
Cenix:122-h9
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:122-h9 (PCR reagent)
Delivery Method	Injection
Remark	Wildtype results in all three tests.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:R11G10.1
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_R11G10.1 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:T10G3.7
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_T10G3.7 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of R11G10.1	*Browse using GBrowse*