Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to R12B2.4Link to R12B2.3RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF R12B2.4 (him-10) Ace View of R12B2.4
R12B2.4 Details Help
GO Terms  meiotic chromosome segregation (GO:0045132) ; mitotic chromosome segregation (GO:0000070) ; mitotic spindle assembly (GO:0007052) ; microtubule/kinetochore interaction (GO:0008608) ; kinetochore (GO:0000776) ; structural molecule activity (GO:0005198)
Location   III:5802809..5805430
RNAi Phenotypes
Early_embryo Cytokinesis defect ; Multiple nuclei in 1, 2, or 4-cell embryos ; P0 spindle positioning defect
Postembryonic WT_postembryonic_morphology
Larva Lva ; Gro
Adult Unc ; Unc ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:R12B2.4
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_R12B2.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_6B1
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Cytokinesis defect
Multiple nuclei in 1, 2, or 4-cell embryos
P0 spindle positioning defect
RNAi Reagent Name & Type sjj_R12B2.4 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Simmer:R12B2.4
Embryonic Phenotypes  Emb Penetrance 100 %
Larval Phenotypes  Gro
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_R12B2.4 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:307H5
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:307H5 (PCR reagent)
Remark  Phenotype comment -- Not yet confirmed by independent RNA
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Cenix:307-h5
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:307-h5 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Gene Plot of R12B2.4 Browse using GBrowse
Gene Map