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Gene/ORF R74.1 (lrs-1) Ace View of R74.1
R74.1 Details Help
Description  lrs-1 encodes a predicted cytoplasmic leucyl-tRNA synthetase (LeuRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of leucine to its cognate tRNA and is thus required for protein biosynthesis; LRS-1 activity is required for embryonic, larval, and germline development, as well as normal body morphology and rates of postembryonic growth.
Homology Group (KOG)  Leucyl-tRNA synthetase
GO Terms  DNA binding (GO:0003677) ; regulation of transcription (GO:0045449) ; leucine-tRNA ligase activity (GO:0004823) ; ATP binding (GO:0005524) ; protein biosynthesis (GO:0006412) ; cytoplasm (GO:0005737) ; tRNA ligase activity (GO:0004812) ; amino acid activation (GO:0006418)
Location   III:4180660..4187172
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects ; Severe Pleiotropic Defects
Larva Lva ; Lva ; Lvl ; Gro
Adult Bmd ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:R74.1 Lva
JA:R74.1 Bmd ; Emb ; Gro ; Lvl ; Ste
Cenix:140-d12 Emb ; Severe Pleiotropic Defects
TH:314a1 Emb
Cenix:314-a1 Emb ; Severe Pleiotropic Defects
Gene Plot of R74.1 Browse using GBrowse
Gene Map