Ace View of R74.1 | |||||||
R74.1 Details | |||||||
Description | lrs-1 encodes a predicted cytoplasmic leucyl-tRNA synthetase (LeuRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of leucine to its cognate tRNA and is thus required for protein biosynthesis; LRS-1 activity is required for embryonic, larval, and germline development, as well as normal body morphology and rates of postembryonic growth. | ||||||
Homology Group (KOG) | Leucyl-tRNA synthetase |
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GO Terms | DNA binding (GO:0003677) ; regulation of transcription (GO:0045449) ; leucine-tRNA ligase activity (GO:0004823) ; ATP binding (GO:0005524) ; protein biosynthesis (GO:0006412) ; cytoplasm (GO:0005737) ; tRNA ligase activity (GO:0004812) ; amino acid activation (GO:0006418) | ||||||
Location | III:4180660..4187172 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Experiments with Non-Wild Phenotypes | |||||||
Simmer:R74.1 | Lva | ||||||
JA:R74.1 | Bmd ; Emb ; Gro ; Lvl ; Ste | ||||||
Cenix:140-d12 | Emb ; Severe Pleiotropic Defects | ||||||
TH:314a1 | Emb | ||||||
Cenix:314-a1 | Emb ; Severe Pleiotropic Defects | ||||||
Gene Plot of R74.1 | |||||||