Ace View of T01B7.7 | |||
T01B7.7 Details | |||
Description | The rol-6 gene encodes a cuticle collagen related to human collagen alpha 1 (III) chain precursor (OMIM:120180), and is required for normal cuticular morphology; ROL-6 interacts with SQT-1, a closely related cuticle collagen, and is expressed at all stages from L2 to adult with transcripts detected at each of the molts preceding these stages. | ||
Homology Group (KOG) | Collagens (type IV and type XIII), and related proteins |
||
GO Terms | cuticle biosynthesis during molting (sensu Nematoda) (GO:0042338) ; extracellular matrix (GO:0005578) ; structural constituent of cuticle (sensu Nematoda) activity (GO:0042329) ; structural constituent of cuticle (GO:0042302) ; phosphate transport (GO:0006817) ; cytoplasm (GO:0005737) | ||
Location | II:8732575..8734639 | ||
RNAi Phenotypes |
|
||
External Links | ![]() ![]() ![]() |
||
Associated RNAi Experiments | |||
Cenix:56-b4 | |||
Adult Phenotypes | WT |
||
RNAi Reagent Name & Type | Cenix:56-b4 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | 3/3 tests are wild type. | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
JA:T01B7.7 | |||
Adult Phenotypes | Dpy Egl |
||
RNAi Reagent Name & Type | sjj_T01B7.7 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Simmer:T01B7.7 | |||
Adult Phenotypes | Dpy |
||
RNAi Reagent Name & Type | sjj_T01B7.7 (PCR reagent) | ||
Laboratory | NL | ||
Date | 2003-10-01 | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Gene Plot of T01B7.7 | |||
![]() |
---|