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Gene/ORF T01B7.7 (rol-6) Ace View of T01B7.7
T01B7.7 Details Help
Description  The rol-6 gene encodes a cuticle collagen related to human collagen alpha 1 (III) chain precursor (OMIM:120180), and is required for normal cuticular morphology; ROL-6 interacts with SQT-1, a closely related cuticle collagen, and is expressed at all stages from L2 to adult with transcripts detected at each of the molts preceding these stages.
Homology Group (KOG)  Collagens (type IV and type XIII), and related proteins
GO Terms  cuticle biosynthesis during molting (sensu Nematoda) (GO:0042338) ; extracellular matrix (GO:0005578) ; structural constituent of cuticle (sensu Nematoda) activity (GO:0042329) ; structural constituent of cuticle (GO:0042302) ; phosphate transport (GO:0006817) ; cytoplasm (GO:0005737)
Location   II:8732575..8734639
RNAi Phenotypes
Adult Dpy ; Dpy ; Egl
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:56-b4
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:56-b4 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wild type.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T01B7.7
Adult Phenotypes  Dpy
Egl
RNAi Reagent Name & Type sjj_T01B7.7 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:T01B7.7
Adult Phenotypes  Dpy
RNAi Reagent Name & Type sjj_T01B7.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of T01B7.7 Browse using GBrowse
Gene Map