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Gene/ORF T03E6.7 (cpl-1) Ace View of T03E6.7
T03E6.7 Details Help
Description  cpl-1 encodes a member of the cathepsin L-like cysteine protease family required for embryonic viability and normal growth; expressed in eggshells and throughout early embryos, accumulates in intestinal cells during late embryogenesis, and expressed in the cuticle, gonad, and pharynx later in development.
Homology Group (KOG)  Cysteine proteinase Cathepsin L
GO Terms  cysteine-type endopeptidase activity (GO:0004197) ; proteolysis and peptidolysis (GO:0006508) ; cysteine-type peptidase activity (GO:0008234)
Location   V:16594756..16598332
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology
Larva Gro ; Gro
Adult Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:T03E6.7
Embryonic Phenotypes  Emb Penetrance 40 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_T03E6.7 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:T03E6.7
Embryonic Phenotypes  Emb Penetrance 20 - 40 %
Larval Phenotypes  Gro
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_T03E6.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Cenix:37-f2
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:37-f2 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No reproducible defects.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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