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Gene/ORF T05C12.7 (cct-1) Ace View of T05C12.7
T05C12.7 Details Help
Description  eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells.
Homology Group (KOG)  Chaperonin complex component, TCP-1 alpha subunit (CCT1)
GO Terms  protein binding (GO:0005515) ; ATP binding (GO:0005524) ; cellular protein metabolism (GO:0044267)
Location   II:8184962..8187926
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects
Larva Lva ; Lva ; Gro
Adult Clr ; Sck ; Pvl ; Sterile F0/Fertility Problems ; Ste ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:202-g3
Adult Phenotypes  Sterile F0/Fertility Problems
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:202-g3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T05C12.7
Embryonic Phenotypes  Emb Penetrance 100 %
Larval Phenotypes  Gro
Adult Phenotypes  Clr
Pvl
Sck
Ste
RNAi Reagent Name & Type sjj_T05C12.7 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:T05C12.7
Embryonic Phenotypes  Emb Penetrance 50 - 80 %
Larval Phenotypes  Lva
Adult Phenotypes  Ste brood size (1 out of 5)
RNAi Reagent Name & Type sjj_T05C12.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of T05C12.7 Browse using GBrowse
Gene Map