ORF Card Page


Gene/ORF T06E4.3 (atl-1)	Ace View of T06E4.3
T06E4.3 Details
Description	The atl-1 gene encodes a large, 2514-residue protein of the ATM family, homologous to human AT (OMIM:208900, mutated in ataxia telangiectasia); the C-terminal sequence of ATL-1 contains a PI-3 kinase-like domain; ATL-1 is required for survival through early embryogenesis and normal chromosomal segregation; atl-1 is expressed in both the mitotic and meiotic cells of adult gonads.
Homology Group (KOG)	Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination
GO Terms	embryonic development (GO:0009790) ; meiotic chromosome segregation (GO:0045132) ; condensed nuclear chromosome (GO:0000794) ; phosphatidylinositol 3-kinase activity (GO:0016303) ; phosphotransferase activity, alcohol group as acceptor (GO:0016773)
Location	V:9637045..9648486
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Details
Cenix:36-f6
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:36-f6 (PCR reagent)
Delivery Method	Injection
Remark	early embryonic: No significant defects.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T06E4.3
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_T06E4.3 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of T06E4.3	*Browse using GBrowse*