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Gene/ORF T07D4.3 (rha-1) Ace View of T07D4.3
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Description  rha-1 encodes an ATP-dependent DEAD/H box RNA helicase orthologous to human RNA helicase A and Drosophila Maleless, an essential component of the dosage compensation machinery required for increased X-linked transcription in males; by homology, RHA-1 is predicted to function in regulation of transcription, translation, RNA processing, and/or RNA replication; in C. elegans, RHA-1 is required for germ cell proliferation, normal germ cell nuclear morphology, RNA-mediated interference (RNAi) of germline-expressed genes, and silencing of germline-expressed transgenes; RHA-1 is reported to localize to the nucleus and the cytoplasm.
GO Terms  negative regulation of gene expression, epigenetic (GO:0045814) ; germ-cell development (GO:0007281) ; RNA interference (GO:0016246) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737)
Location   II:8878019..8883973
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:202-a4 WT
JA:T07D4.3 WT
PF:GL1_2D11 WT
Gene Plot of T07D4.3 Browse using GBrowse
Gene Map