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Gene/ORF
T10B5.6 (knl-3)
Ace View of T10B5.6
T10B5.6 Details
Location
V:1868642..1870720
RNAi Phenotypes
Early_embryo
P0 spindle does not rotate
;
Multiple maternal pronuclei
;
Multiple cavities
;
Chromosome Segregation (karyomeres) abnormal
;
Multiple nuclei in 1, 2, or 4-cell embryos
;
Cytokinesis defect
;
Excessive blebbing
;
Abnormal size of pronucleus
;
Large cytoplasmic granules
;
Nuclei reform next to cell division remnant
Adult
Pvl
;
Unc
;
Unc
External Links
Associated RNAi Experiments
View Summary
Cenix:143-e3
Embryonic Phenotypes
Emb
Penetrance None reported
Adult Phenotypes
Chromosome Segregation (karyomeres) abnormal
RNAi Reagent Name & Type
Cenix:143-e3 (PCR reagent)
Delivery Method
Injection
Remark
early embryonic: Chromosome Segregation (karyomeres)
Laboratory
TH
Date
2005-3-24
Reference
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T10B5.6
Embryonic Phenotypes
Emb
Penetrance 100 %
Adult Phenotypes
Unc
RNAi Reagent Name & Type
sjj_T10B5.6 (PCR reagent)
Laboratory
JA
Date
2003-1-10
Reference
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_4F2
Embryonic Phenotypes
Emb
Penetrance 100 %
Adult Phenotypes
Abnormal size of pronucleus
Cytokinesis defect
Excessive blebbing
Large cytoplasmic granules
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
P0 spindle does not rotate
RNAi Reagent Name & Type
sjj_T10B5.6 (PCR reagent)
Delivery Method
Injection
Remark
PCR product contains flanking T7 promoter sequences
Laboratory
KK
Date
2002-11-19
Reference
Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images
Simmer:T10B5.6
Embryonic Phenotypes
Emb
Penetrance 100 %
Adult Phenotypes
Pvl
Unc
RNAi Reagent Name & Type
sjj_T10B5.6 (PCR reagent)
Laboratory
NL
Date
2003-10-01
Strain
NL4256 rrf-3(pk1426)
Reference
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of T10B5.6
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