Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to T10B5.6Link to T10B5.4RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF T10B5.6 (knl-3) Ace View of T10B5.6
T10B5.6 Details Help
Location   V:1868642..1870720
RNAi Phenotypes
Early_embryo P0 spindle does not rotate ; Multiple maternal pronuclei ; Multiple cavities ; Chromosome Segregation (karyomeres) abnormal ; Multiple nuclei in 1, 2, or 4-cell embryos ; Cytokinesis defect ; Excessive blebbing ; Abnormal size of pronucleus ; Large cytoplasmic granules ; Nuclei reform next to cell division remnant
Adult Pvl ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:143-e3
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Chromosome Segregation (karyomeres) abnormal
RNAi Reagent Name & Type Cenix:143-e3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Chromosome Segregation (karyomeres)
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T10B5.6
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_T10B5.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_4F2
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Abnormal size of pronucleus
Cytokinesis defect
Excessive blebbing
Large cytoplasmic granules
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
P0 spindle does not rotate
RNAi Reagent Name & Type sjj_T10B5.6 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Simmer:T10B5.6
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Pvl
Unc
RNAi Reagent Name & Type sjj_T10B5.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of T10B5.6 Browse using GBrowse
Gene Map