Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to T13H10.1RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF T13H10.1 (kin-5) Ace View of T13H10.1
T13H10.1 Details Help
Description  kin-5 encodes a predicted protein tyrosine kinase that is most closely related to the non-receptor tyrosine kinases Fes/Fps and Fer that contain an SH2 domain and a tyrosine kinase domain (OMIM:190030, murine Fes appears to be required for hemopoietic homeostasis); as loss of kin-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kin-5 in C. elegans development and/or behavior is not yet known.
Homology Group (KOG)  Protein tyrosine kinase
GO Terms  protein kinase activity (GO:0004672) ; ATP binding (GO:0005524) ; protein amino acid phosphorylation (GO:0006468) ; intracellular signaling cascade (GO:0007242) ; protein-tyrosine kinase activity (GO:0004713)
Location   IV:9966677..9969552
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:13-e4
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:13-e4 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Overall wildtype. Subtle defects in nuclear migration and rotation suggest a possible MT/cortex interaction problem, however, none of the defects shows any consequences up to the 4 cell stage.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:T13H10.1
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_T13H10.1 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of T13H10.1 Browse using GBrowse
Gene Map