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Gene/ORF T20H4.4 (adr-2) Ace View of T20H4.4
T20H4.4 Details Help
Description  adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis.
Homology Group (KOG)  tRNA-specific adenosine deaminase 1
GO Terms  RNA binding (GO:0003723) ; adenosine deaminase activity (GO:0004000) ; RNA processing (GO:0006396) ; double-stranded RNA binding (GO:0003725) ; intracellular (GO:0005622)
Location   III:7230488..7233208
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:305-b3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_T20H4.4 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:305B3 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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