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Gene/ORF T21E12.4 (dhc-1) Ace View of T21E12.4
T21E12.4 Details Help
Description  dhc-1 encodes a cytoplasmic dynein heavy chain homolog required in one-cell embryos for pronuclear migration, centrosome separation, centrosome proximity to the male pronucleus, and mitotic spindle orientation, suggesting that DHC-1 helps position the microtubule organizing center; DHC-1 genetically interacts with SPD-5, a coiled-coil centrosomal protein.
Homology Group (KOG)  Dyneins, heavy chain
GO Terms  nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; microtubule motor activity (GO:0003777) ; microtubule-based movement (GO:0007018) ; dynein complex (GO:0030286)
Location   I:4386391..4402381
RNAi Phenotypes
Early_embryo Pnm ; Pnm
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:T21E12.4:Screen_A Emb
Cenix:143-c5 Emb ; Pnm
JA:T21E12.4 Emb ; Pnm
Gene Plot of T21E12.4 Browse using GBrowse
Gene Map