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Gene/ORF T22F3.3 Ace View of T22F3.3
T22F3.3 Details Help
Description  T22F3.3 is orthologous to the human gene MUSCLE GLYCOGEN PHOSPHORYLASE (PYGM; OMIM:232600), which when mutated leads to McArdle disease.
Homology Group (KOG)  Glycogen phosphorylase
GO Terms  phosphorylase activity (GO:0004645) ; pyridoxal phosphate binding (GO:0030170) ; carbohydrate metabolism (GO:0005975)
Location   V:3578472..3585259
RNAi Phenotypes
Early_embryo Slow cell cycle ; Cytokinesis defect ; Large cytoplasmic granules ; EMS fails to extend anteriorly ; Multiple nuclei in 1, 2, or 4-cell embryos
Postembryonic WT_postembryonic_morphology
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:F40C5.a
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.a (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F40C5.b
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.b (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F40C5.c
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.c (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F40C5.d
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.d (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F40C5.e
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.e (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F40C5.h
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F40C5.h (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:T22F3.3
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_T22F3.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_1H6
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Cytokinesis defect
EMS fails to extend anteriorly
Large cytoplasmic granules
Multiple nuclei in 1, 2, or 4-cell embryos
Slow cell cycle
RNAi Reagent Name & Type sjj_T22F3.3 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Cenix:76-f1
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:76-f1 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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