| Ace View of T25C8.2 | |||||||
| T25C8.2 Details | |||||||
| Description | an ortholog of human cytoplasmic actin; and is expressed only in microvillous intestinal cells and excretory cell. | ||||||
| Homology Group (KOG) | Actin and related proteins |
||||||
| GO Terms | motor activity (GO:0003774) ; structural constituent of cytoskeleton (GO:0005200) ; actin filament (GO:0005884) ; protein binding (GO:0005515) | ||||||
| Location | III:13603455..13605984 | ||||||
| RNAi Phenotypes |
|
||||||
| External Links |    |
||||||
| Associated RNAi Experiments | |||||||
| Cenix:321-e6 | |||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||
| Adult Phenotypes | Asymmetry of Division abnormal |
||||||
| RNAi Reagent Name & Type | Cenix:321-e6 (PCR reagent) | ||||||
| Delivery Method | Injection | ||||||
| Remark | early embryonic: Asymmetry of Division | ||||||
| Laboratory | TH | ||||||
| Date | 2005-3-24 | ||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
| Cenix:340-f5 | |||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||
| Adult Phenotypes | Asymmetry of Division abnormal |
||||||
| RNAi Reagent Name & Type | Cenix:340-f5 (PCR reagent) | ||||||
| Delivery Method | Injection | ||||||
| Remark | early embryonic: Asymmetry of Division | ||||||
| Laboratory | TH | ||||||
| Date | 2005-3-24 | ||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
| Simmer:T25C8.2 | |||||||
| Adult Phenotypes | Ste |
||||||
| RNAi Reagent Name & Type | sjj_T25C8.2 (PCR reagent) | ||||||
| Laboratory | NL | ||||||
| Date | 2003-10-01 | ||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
| TH:321E6 | |||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||
| RNAi Reagent Name & Type | TH:321E6 (PCR reagent) | ||||||
| Remark | Phenotype comment -- Confirmed with independent dsRNA (T25C8.2-RNA2; similar, albeit perhaps weaker, phenotype). Phenotype could potentially be due to cross-RNAi inhibition of other actin genes (see BLASTN results). However, T25C8.2-RNA2 was designed to minimize cross-RNAi | ||||||
| Laboratory | TH | ||||||
| Date | 2000-11-16 | ||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||
| TH:340F5 | |||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||
| RNAi Reagent Name & Type | TH:340F5 (PCR reagent) | ||||||
| Remark | Phenotype comment -- Confirmed with independent dsRNA (T25C8.2-RNA2; similar, albeit perhaps weaker, phenotype). Phenotype could potentially be due to cross-RNAi inhibition of other actin genes (see BLASTN results). However, T25C8.2-RNA2 was designed to minimize cross-RNAi | ||||||
| Laboratory | TH | ||||||
| Date | 2000-11-16 | ||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||
| Gene Plot of T25C8.2 | |||||||
|
|||||||
|---|---|---|---|---|---|---|---|
![Adult](JavaScript:void
window.open("/cgi-bin/rnaidb/popUpImage.cgi?imgName=N2wormfinal.png",
"RNAiDB Help","toolbar=no, location=no, directories=no,
status=no, menubar=no, scrollbars=yes, resizable=no,
copyhistory=no, width=1000, height=550"))
 |
Please provide feedback if you are experiencing any difficulties with this website. |