Ace View of T26A5.9 | |||||||||
T26A5.9 Details | |||||||||
Description | dlc-1 encodes a dynein light chain type 1 that affects pronuclear migrations and thus affects embryonic viability; also affects fertility, body wall morphology and integrity. | ||||||||
Homology Group (KOG) | Dynein light chain type 1 |
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GO Terms | microtubule motor activity (GO:0003777) ; microtubule-based process (GO:0007017) ; microtubule associated complex (GO:0005875) | ||||||||
Location | III:6462444..6464138 | ||||||||
RNAi Phenotypes |
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External Links | |||||||||
Associated RNAi Experiments | |||||||||
Cenix:330-f1 | |||||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
Adult Phenotypes | Pnm |
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RNAi Reagent Name & Type | Cenix:330-f1 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Remark | early embryonic: Pronuclear Migration | ||||||||
Laboratory | TH | ||||||||
Date | 2005-3-24 | ||||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
TH:310E9 | |||||||||
Adult Phenotypes | WTDIC phenotype -- Embryonic development normal |
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RNAi Reagent Name & Type | TH:310E9 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Laboratory | TH | ||||||||
Date | 2000-11-16 | ||||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
TH:311F2 | |||||||||
Adult Phenotypes | WTDIC phenotype -- Embryonic development normal |
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RNAi Reagent Name & Type | TH:311F2 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Laboratory | TH | ||||||||
Date | 2000-11-16 | ||||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
TH:330F1 | |||||||||
Adult Phenotypes | WTDIC phenotype -- Embryonic development normal |
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RNAi Reagent Name & Type | TH:330F1 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Laboratory | TH | ||||||||
Date | 2000-11-16 | ||||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
Cenix:309-d6 | |||||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
Adult Phenotypes | Pnm |
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RNAi Reagent Name & Type | Cenix:309-d6 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Remark | early embryonic: Pronuclear Migration | ||||||||
Laboratory | TH | ||||||||
Date | 2005-3-24 | ||||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
Cenix:340-e6 | |||||||||
RNAi Reagent Name & Type | Cenix:340-e6 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Laboratory | TH | ||||||||
Date | 2005-3-24 | ||||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
JA:T26A5.9 | |||||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||||
Adult Phenotypes | Bmd Dpy Rup Ste |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Laboratory | JA | ||||||||
Date | 2003-1-10 | ||||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||||
Simmer:T26A5.9 | |||||||||
Embryonic Phenotypes | Emb Penetrance 90 % | ||||||||
Larval Phenotypes | Gro |
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Adult Phenotypes | Bmd Dpy Pvl Unc |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Laboratory | NL | ||||||||
Date | 2003-10-01 | ||||||||
Strain | NL4256 rrf-3(pk1426) | ||||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||||
TH:309d6 | |||||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
RNAi Reagent Name & Type | TH:309d6 (PCR reagent) | ||||||||
Remark | Phenotype comment -- Confirmed with independent dsRNA (T26A5.9-RNA2; ; similar phenotype) as well as by Chris Shelton and Bruce Bowerman (personal communication). | ||||||||
Laboratory | TH | ||||||||
Date | 2000-11-16 | ||||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
TH:340e6 | |||||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
RNAi Reagent Name & Type | TH:340e6 (PCR reagent) | ||||||||
Remark | Phenotype comment -- Confirmed with independent dsRNA (T26A5.9-RNA2; ; similar phenotype) as well as by Chris Shelton and Bruce Bowerman (personal communication). | ||||||||
Laboratory | TH | ||||||||
Date | 2000-11-16 | ||||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
WBRNAi00060086 | |||||||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Delivery Method | Bacterial_feeding | ||||||||
Laboratory | KP | ||||||||
Date | 2005-5-09 | ||||||||
Reference | Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." | ||||||||
WBRNAi00060087 | |||||||||
Adult Phenotypes | aldicarb_resistant
Animals displayed resistance to paralysis on aldicarb in 4 out of 8 trials. |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Delivery Method | Bacterial_feeding | ||||||||
Laboratory | KP | ||||||||
Date | 2005-5-09 | ||||||||
Reference | Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." | ||||||||
WBRNAi00060088 | |||||||||
Larval Phenotypes | Let |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Delivery Method | Bacterial_feeding | ||||||||
Laboratory | KP | ||||||||
Date | 2005-5-09 | ||||||||
Reference | Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." | ||||||||
WBRNAi00060089 | |||||||||
Larval Phenotypes | Let |
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RNAi Reagent Name & Type | sjj_T26A5.9 (PCR reagent) | ||||||||
Delivery Method | Bacterial_feeding | ||||||||
Laboratory | KP | ||||||||
Date | 2005-5-09 | ||||||||
Reference | Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." | ||||||||
Cenix:310-e9 | |||||||||
Adult Phenotypes | Pnm WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:310-e9 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Remark | early embryonic: Pronuclear Migration | ||||||||
Laboratory | TH | ||||||||
Date | 2005-3-24 | ||||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
Cenix:311-f2 | |||||||||
Adult Phenotypes | Pnm WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:311-f2 (PCR reagent) | ||||||||
Delivery Method | Injection | ||||||||
Remark | early embryonic: Pronuclear Migration | ||||||||
Laboratory | TH | ||||||||
Date | 2005-3-24 | ||||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
Gene Plot of T26A5.9 | |||||||||