Gene/ORF
T28F12.2 (unc-62)
|
Ace View of T28F12.2
|
T28F12.2 Details |
|
Description |
unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles. |
GO Terms |
DNA binding
(GO:0003677) ; transcription factor activity
(GO:0003700) ; regulation of transcription, DNA-dependent
(GO:0006355) ; nucleus
(GO:0005634) ; regulation of transcription
(GO:0045449) |
Location |
V:4496877..4511657 |
RNAi Phenotypes |
|
External Links |
|
Associated RNAi Experiments |
View Details
|
Experiments with Non-Wild Phenotypes |
Simmer:T28F12.2a |
Emb |
Cenix:155-e10 |
Emb ; WT_postembryonic_morphology |
JA:T28F12.2a |
Dpy ; Egl ; Emb ; Unc |
Gene Plot of T28F12.2 |
Browse using GBrowse
|
|